Chromatography

When it comes to media support, our porous plastic technologies are the leading choice for applications in process chromatography, flash chromatography and Solid Phase Extraction (SPE) markets.

Solid Phase Extraction (SPE) Frits

Recognised as a world leading material in  SPE frits, Porvair Sciences’ Vyon® is an excellent choice as support media in sample preparation. It provides support for loose-packed resins and is designed for optimum flow; an essential property to enable maximum efficiency interaction of the resins with compounds. Alternatively, resins can be immobilised within the chemically inert Vyon® matrix providing improved recovery and unrivalled reproducibility in sample preparation.  

Using our highly-skilled and cross-functional experience, Porvair Sciences has developed its own range of fully assembled SPE solutions. To find out more about our Microlute® assembled plates and cartridges, which incorporate this unique composite technology, please click here.

SPE Frits
  • Fully customisable 
  • Excellent frit-to-frit consistency 
  • Low leachables and low particle shedding 
  • Suitable for sterilisation by ethylene oxide and gamma radiation 
  • Rigid and easy to assemble in mass production 
  • Manufactured to tight tolerances with an excellent edge-finish 
  • Manufactured from regulatory approved polymers
  • Polyethylene (HDPE & UHMWPE)
  • Polytetrafluoroethylene (PTFE)
  • PE-Silica Resin Composite
  • PE-Polymeric Resin Composite
  • Polypropylene (PP)
  • Hydrophilic Treatment
  • Ultraclean Treatment

Vyon® SPE Disc products are typically supplied in the following geometries but are fully customisable to your requirements.  

  • Cut Discs 
  • Moulded Shapes (including spheres) 
  • Fully Assembled Plates and Cartridges 

Flash Chromatography Frits

Flash chromatography is a rapid purification technique. Vyon® materials are an excellent resin support for flash chromatography columns as they can be designed to ensure no breakthrough of the finer resins typically used in this application.

Flash Chromatography Discs
  • Fully customisable
  • Excellent frit-to-frit consistency
  • Low leachables and low particle shedding
  • Suitable for sterilisation by ethylene oxide and gamma radiation
  • Rigid and easy to assemble in mass production
  • Manufactured to tight tolerances with an excellent edge-finish
  • Manufactured from regulatory approved polymers 
  • Polyethylene (HDPE & UHMWPE)
  • Polytetrafluoroethylene (PTFE)
  • Polypropylene (PP)
  • Hydrophilic Treatment
  • Ultraclean Treatment 

Vyon® Flash Chromatography Support Media is typically supplied in the following geometries but are fully customisable to your requirements.  

  • Cut Discs
  • Machined Discs and Shapes 

Process Chromatography Bed Supports

Vyon® advanced porous plastics are perfectly suited as a resin support media in the isolation and purification of pharmaceutical drug production. Strong and firm support with uniform flow is a prerequisite for these applications. 

As columns size can vary, requiring up to 2m in diameter, we can custom manufacture to fit all proprietary column designs. The larger diameter disc supports are manufactured in a cGMP clean and temperature-controlled environment to achieve the tight tolerances required for this application. 

Process Chromatography Bed Supports
  • Fully customisable
  • Manufactured to tight tolerances with an excellent edge-finish
  • Rigid and easy to assemble into your column design
  • Manufactured from regulatory approved polymers with European Pharmacopoeia and USP 88 Class VI available on selected grades
  • Polyethylene (HDPE & UHMWPE)
  • Hydrophilic Treatment 

Vyon® Process Chromatography Bed Supports are typically supplied in the following geometries but are fully customisable to your requirements.

  • Machined Discs and Shapes